The latest issue of Game Informer has details on 3D Realms' Earth No More, likely one of their two "big announcements" expected within the next six months. The title is being developed for PC, Xbox 360 and PlayStation 3 by Recoil Gamers, reportedly made up of former Max Payne developers.
Earth No More centers around a New Englander caught in the middle of an outbreak in a town surrounded by poison, terraforming vines -- it may sound a lot like War of the Worlds, but these vines are (gasp!) part of a man-made catastrophe!
The game will play out without cutscenes, à la Half-Life 2, and the article (via CVG) claims that human interaction will be the focus of the title, "with a conversation mechanic said to rival that of Mass Effect." Bit of a bold statement, given that BioWare's RPG is still not finalized (or dated, for that matter). There will also be online co-op.
Earth No More is tentatively set for a 2009, or 12 A.D. (i.e. After Duke Nukem Forever was announced), release.