upcoming Fallout 3 DLC, MTV's Stephen Totilo grabbed his brass knuckles, donned his fedora with the "Press" card tucked under the band and pounded on the e-door of PR man Pete Hines until he gave up some answers.
In terms of scope, it looks like you'll want to (sadly) think smaller than Oblivion's massive Shivering Isles and more along the lines of Knights of the Nine, which ran $9.99. Also, it looks like you'll access the new stuff in-game rather than through a menu (à la Oblivion.)
That's pretty much all Totilo managed to get out of Hines, even though he tuned the poor guy up pretty good. Where'd he learn to fight like that? Why, from the best, of course.