Prior to the Razer DeathAdder Mac Edition in 2008, all Razer mice and peripherals only had native Windows support and drivers. While these products would generally work with a Mac through its plug-and-play technology, customizing them was more difficult and in some cases, impossible. In order to configure my Razer Lachesis to make all its buttons usable on my Mac, I had to configure it on a PC and mapped some of the buttons as little used keyboard keys because the Mac wouldn't recognize click-throughs from more than a few mouse buttons.
This situation improved with the release of the Razer Naga, which shipped with native Mac support, although the key-mapping functionality for the Mac came several weeks after the PC version. Currently, newer mice come with basic Mac support, although Razer promises the same functionality and customizability as their PC counterparts through future updates. Razer also promises to release Mac drivers for all existing products, which presumably includes their line of headsets and keyboards. While Mac gamers have always been treated as second class citizens by most peripheral manufacturers, it's encouraging to see a major player pay the community some attention. I mean, the Magic Mouse is awesome and all, but there's nothing like having a real gaming mouse to play WoW.