For helping everyone figure out what to do while waiting for Devil May Cry 4 to install on our PlayStation 3, Penny Arcade earns major kudos and top honors as this week's best game-related webcomic. Personally, we opted for their final suggestion. (
As noted by reader Special_K, the second panel is actually Hindi. Strange continuity error for the linguistic-obsessed Tycho.) (Nevermind, we were fooled. Thanks, Sam!)
Second place went to Digital Unrest while third was claimed by Monday Night Crew (originally called "No more potty training" due to HTML errors, but linked to "The Legend Never Dies"). Thanks to everyone who voted, and be sure to let us know of any game-related webcomics you stumble upon this week!