This doesn't mean developers are completely helpless; indeed, as the comments pointed out, there is stuff that can be done to thwart IPA cracking and even the use of Crackulous itself. But what if you are just struggling to find time to code your current iPhone projects and don't have the time or necessary skill-level to address iPhone piracy?
Enter Ripdev's new Kali Anti-Piracy service. I talked to Slava from Ripdev last week, and they really seem to be onto something. Essentially, Ripdev has figured out how to put an extra wrapper around iPhone apps, which not only prevents the app from launching or functioning properly if it has been cracked, but also prevents the current cracking tools from working on the app at all. Even better, this process only uses documented and allowed calls, making it SDK compliant. Oh -- and if the app is legitimately purchased, it can run on a jailbroken iPhone without a problem.