Platinum Games' Shigenori Nishikawa, the director on MadWorld for the Wii, has told Official Nintendo Magazine that he wouldn't mind taking a second crack at the violent Wii game. "I think MadWorld was very well received and was acknowledged for its innovative graphical style and gameplay," Nishikawa said in Friday's upcoming issue. "We would definitely be interested in making a sequel in the future."
Of course, you might have a tough time believing that Sega would also be on board. The company has said it would probably not be interested in more mature Wii games, which means Platinum Games would have to shop around for a new publisher first.