P.L.E.A.S.E. is the polite and painless way to deliver drugs with lasers
By Tim Stevens 
posted June 3rd 2010 9:34AM
posted June 3rd 2010 9:34AM
Pantec Biosolutions' P.L.E.A.S.E. Professional® Receives Marketing Authorisation
Tuesday, June 1, 2010 12:00 am
Ruggell, Liechtenstein, 1 June 2010- Pantec Biosolutions AG, a privately-owned company developing innovative technologies for transdermal drug delivery, today announced that it has received a CE mark in the EU for the new professional product line of the Company's transdermal delivery device: P.L.E.A.S.E.® (Painless Laser Epidermal System).
P.L.E.A.S.E. Professional® is an affordable portable benchtop system with a diode pumped Er:YAG fractional ablative laser. Compared with the currently marketed lamp pumped systems, P.L.E.A.S.E. Professional® is a small, lightweight and very cost efficient device with a variety of applications in conventional and aesthetic dermatology and in general medicine. P.L.E.A.S.E. Professional® allows precise intraepidermal microporation in connection with improved transdermal drug delivery of new or existing drugs. This class 1 laser device requires little maintenance and clinicians using it have no need for safety protection.
"P.L.E.A.S.E.® has already demonstrated its clinical utility and we are delighted now to have a CE Mark that will allow us to make the technology available widely in the form of P.L.E.A.S.E. Professional®," said Christof Boehler, CEO of Pantec Biosolutions. "This is an important milestone for Pantec as this device will unlock therapeutic areas with high unmet need for easy-to-use, efficient, and painless application of biologicals. We plan to start a number of clinical studies looking at a variety of applications in the coming months including trials looking at the more efficient delivery of small molecule drugs."
The rigorous audit that must be completed before awarding a CE Mark is based on a conformity assessment procedure and thoroughly scrutinizes product development and production documentation to ensure compliance to the medical device directive (MDD). Medical devices are required to bear a CE mark before they can be sold in member countries of the European Economic Area (EEA).
About Pantec Biosolutions and P.L.E.A.S.E.®
Pantec Biosolutions AG is a private drug delivery company specialised in using laser microporation technology to deliver large molecular weight drugs into the epidermis for local or systemic uptake. Its proprietary P.L.E.A.S.E.® (Painless Laser Epidermal System) platform enables efficient, needle-free and painless administration of biopharmaceutical drugs, in varying and individualised dosages, through partnered patch technology. The technology is currently in clinical trials for the delivery of IVF hormone therapy, a market with an estimated value of US$1.5 – 2 billion.
Pantec Biosolutions' P.L.E.A.S.E.® platform is available both for the development of the Company's own pipeline and for penetration into new markets through strategic partnerships. Pantec Biosolutions is based in Ruggell, Liechtenstein.
Just placed my preorder!
awwww, so no more stimpacks?
One step closer to Star Trek type medication!!!!
@gargle Up next, Phasers from the same company, in the same form-factor.
@Chopes
Funny coincidence:
"WORTHING, England, June 1 (UPI) -- A doctor at a British hospital said a new rule requiring doctors to write "please" on blood test request forms could put patients at risk.
Administrators at England's Worthing Hospital confirmed the new policy of refusing blood tests during weekends if doctors have not written "please" on the form, The Sun reported Tuesday."
http://www.upi.com/Odd_News/2010/06/01/Doctor-slams-hospitals-please-policy/UPI-74391275418409/
Finally...an easy and painless way to continue my heroin addiction.
P.U.L.S.E. Disc 2 is the way to zone out after using this thing.
@matty
Get real, mixing it in to Healthy Choice meals is much more healthy for you.
SHOOP DA WHOOP!
Hypospray anyone?
@VTTony EXACTLY what I was thinking! I love it when Trek tech becomes real!
@42 Well, it's not exactly Trek Tech, you have to put up a patch after the laser things, but still, awesome awesome awesome!
I wonder what the absorption rate is...it probably compares to any sub-q injection...seems pretty stupid to me. a 29 or 30 guage needle you can barely feel at all.
@DoctarPeppar
I wonder if you'll have burn marks or scars from this thing. Or if you'll end up with Chimera from MI:2
@DoctarPeppar Speak for yourself... some of us just HATE needles. Trypanophobia, according to Wikipedia. Sounds like a fear of trepanation, which is to brain surgery what needles are to this doohickey.
@jjsavage
I don't understand the fear of needles...large guage needles, yeah, those are a bitch but smaller guaged like 29 or 30 are so thin and so small that it's like a bee sting, not even...
@DoctarPeppar tell that to a diabetic who needs to use them 4-5 times per day.
@DoctarPeppar
Its not about the pain, its about the hygiene - the possible needle cross infection. So what's more hygienic that a beam of light!?
.
Indeed, we are already developing technology used in fictional SciFi TV progs! Awesome!
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Does it make a 'Pfffssst' sound!?
@cicada
I used to use needles like 20-30 times per day (for undisclosed reasons :P)
@Heliosphan
Good point -- hadn't thought of that, but it looks like this tech won't replace IV injections anytime soon, just Sub-q.
@DoctarPeppar no pain versus bee sting...hmmmm
@cicada
Yup. Insulin can't be used in 'patch' form right now because the molecules are too large to penetrate the skin. This is exactly the tech that several researchers have been working on the make insulin patches a possibility. Dosing the insulin properly is another issue though. A pump is still required.
@DoctarPeppar
It's not the fear from pain... hese days it's not going to pain so much, yeah I know but I still have fear of needles.
The last E? What about the A?
@bravokiloromeo They just felt like throwing letters in there to make it sound cool :D
@unknownsolo a silent A, typed, but not pronounced,,lol
Pew pew!!
Skynets just trying to condition use to ask to be shot by lasers. Don't do it, it's a trick.
@KAL326 Does that mean that it gonna run android then? I was actually hoping HP would put WebOS on it :/
Is there anything that lasers can't do?!
@Davo
Be mounted on sharks apparently...
@Davo They currently can't blow up entire solar systems. But don't worry, I have a team of crackpot Scientroopers working on Technology to solve that
I wonder what the range is on this thing? Like could I tranq someone from a good distance away?
Lasers are all fine and dandy, but everyone knows that the real benefit from getting shots isn't the drug itself, but the character you build by being jabbed with needles. Duh. Now we're just building a society of well-inoculated sissies.
@kevout
+1
LMAO! On the far right, under Wargadget, it shous the article for the Boeing 747 that destroyed a ballistic missile with a laser, lol. Ironic...
Umm... no lasers for my arse though.
This made me more comfortable with the idea of taking steroids
I
Sign me up!
Do you expect me to talk?
No, Mr Bond, I expect you to die!
Ps: when will we get this on the NHS?
Damn it Jim, I'm a doctor! With a freekin lazer.
For a company that created what looks to be the best damned thing since the invention of the wheel for diabetics, they need a lesson in choosing a web host that can scale to influx of traffic. The site and video is a no go.
If they can deliver insulin this way I would try it out. Not because I'm afraid of needles (I'm actually quite used to them) but because it might minimize the scar tissue that builds up over time. My insulin pump is terrible about leaving scar tissue under my skin and it's only going to get worse.
@Vaughanabe13 unfortunately the scar tissue comes more from the insulin injected rather than the needle or cannula. The pump is 'worse' because you're dumping it all in the same spot, consistently, for a couple of days at least. I don't see that this would change that much, not to mention that you'd probably have to hold it in place for a pretty long time to absorb a normal bolus.
@cicada Ugh, I know you're right, but it still sucks. I think I actually like taking insulin injections more than using the pump, but my long-time insulin (Lantus) wasn't doing a good job keeping my BG down in the night. The pump fixes that problem but creates many others, like the scar tissue. Plus, I'm allergic to all of the adhesives on the infusion sets so I have to take a daily allergy pill to prevent hive breakouts.
Definitely a better way to drug someone if you're hitman
Wow this technology is crazy. almost as crazy as apple withdrawing unlimited service and all other data companies thinking of doing the same thing :( it's true according to this article http://bit.ly/cFdq9e
@investmentrep when did Apple start delivering data service?
And a whole new way of dosing perspective friends/rape victims for shits and giggles.
@A25i
prospective***