CaliforniaInstituteOfTechnology

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  • Qian Laboratory

    The world's smallest Mona Lisa is made from DNA

    by 
    Jon Fingas
    Jon Fingas
    12.06.2017

    Leonardo da Vinci's Mona Lisa painting isn't actually that big (30 inches tall), but Caltech researchers have found a way to make that seem downright gargantuan. They've used DNA to construct the smallest known Mona Lisa. At several hundred nanometers across, they're roughly as large as a lone E. coli bacterium -- the iconic smile is just 100nm wide. The trick was an adaptation of a DNA "origami" method that got the gene strands to fold and assemble into the right shape.

  • Demin Liu/Caltech

    DNA 'robots' could sort molecules in your blood

    by 
    Jon Fingas
    Jon Fingas
    09.18.2017

    Robots are already good at sorting things, so wouldn't it be nice if they could sort things out on a much smaller scale? They might soon. Caltech researchers have developed a 'robot' made from a single DNA strand that autonomously picks up molecules and moves them to specific places. It certainly doesn't look like a machine (what you're seeing above is merely representative), it behaves like one. Each segment is a collection of nucleotides that automatically performs a specific task: one segment tells the bot where to go, while separate limbs help it move around and grab molecules.

  • Watch the Milky Way's birth in this Caltech simulation

    by 
    Mariella Moon
    Mariella Moon
    09.11.2016

    A team of Caltech astronomers created what could be the most accurate computer simulation of our galaxy's birth. See, according to computations for older simulations, our galaxy should be surrounded by thousands of dwarf galaxies. In reality, though, there are only around 30 dwarf galaxies nearby. Astronomers thought their computations were incorrect, because we still don't understand the true nature of dark matter that permeates every corner of the universe. However, the Caltech team found out that it's not dark matter that's the problem. Their computations were able to achieve the current state of our galaxy simply by incorporating the effects of supernovae.

  • Molecules in space may show how life formed on Earth

    by 
    Jon Fingas
    Jon Fingas
    06.15.2016

    Scientists have known for a while that the molecular ingredients of life can be found in nearby comets and meteorites, but it's now clear that those building blocks exist much, much further away from home. A research team has used spectral analysis to discover evidence of organic chiral molecules, the "mirror-image" molecules that are key to biology as we know it, in the Sagittarius B2 cloud near the heart of the Milky Way. This doesn't meant that life is forming in space, but it does suggest that the necessary molecular properties can appear in space first and transfer to planets through meteorite impacts.

  • Astronomers may have found the Solar System's 9th planet

    by 
    Andrew Tarantola
    Andrew Tarantola
    01.20.2016

    Astronomers from the California Institute of Technology (CIT) announced on Wednesday that they have found evidence to suggest that our solar system does indeed have a ninth planet -- a rather enormous one at that. This as-of-yet unnamed planet, which is being referred to as "Planet Nine" for the time being, is thought to be between five and ten times the size of the Earth and orbits so far beyond Pluto that it circles the sun just once every 10,000 to 20,000 years.

  • Physics' best-known lectures are now available to everyone on the web

    by 
    Jon Fingas
    Jon Fingas
    09.01.2014

    Ask professors about important physics lectures, and they'll probably point you toward Richard Feynman's famous 1964 talks. They led to one of the most popular physics books ever (over 1.5 million English copies sold) and helped generations understand concepts like quantum mechanics. They've been available to the public for a few years now, but there hasn't been an easy, legal way to read them online... until now, that is. The California Institute of Technology has finished publishing Feynman's lectures in a free, HTML5-based viewer that lets you read on any device with a modern web browser. Even the equations and diagrams are visible on small screens. You're sadly not allowed to grab offline copies, but these web versions may be perfect for brushing up on the fundamentals of energy and matter before a big test -- even if you have to study on your smartphone. [Image credit: Associated Press]

  • Researchers turn standard microscope into billion-pixel imaging beast

    by 
    Melissa Grey
    Melissa Grey
    07.29.2013

    A team of researchers at the California Institute of Technology, led by Professor Changhuei Yang, have figured out a way to crank their microscopy up to 11. Usually, scientists are forced between a rock and a hard place: they can have high res images of small areas or low resolution pictures of larger fields. Using a strategy known as Fourier ptychographic microscopy, Yang's team was able to computationally correct a standard microscope's low res imagery, producing a billion-pixel picture. By adding an LED array to an existing microscope -- the only hardware tweak their $200 system calls for -- the researchers were able to stitch together a 20X quality image from a 2X optical lens. The information gleaned from the LED lights was corrected entirely on a computer, making it an exceptionally cost effective way to create high res microscopic images. The team's report, published by the journal Nature Phototonics, can be read in full at the source link below.

  • Caltech self-healing chips can recover from laser blasts, save power while healthy

    by 
    Jon Fingas
    Jon Fingas
    03.09.2013

    While many scientists have heard the call for self-healing electronics, their previous projects have usually had just a limited capacity to come back from the brink. Caltech has developed an integrated circuit that could take much more of a bruising. Its prototype power amplifier chip has a dedicated circuit and sensors that can change actuators in microseconds if there's damage, re-optimizing the connections on the spot. And the chip can take a lot of that damage -- 76 examples in a penny-sized cluster endured multiple laser strikes in tests (like the one above) while still ticking. The self-healing even helps while everything is in tip-top shape, as it can cut power use by watching for the usual hiccups in load and voltage. So long as Caltech can develop the technology beyond its currently expected niches of communication and imaging, many of our computing devices could eventually take a few bumps and scrapes on the inside, not just their rugged exteriors.

  • Caltech laser accelerometer research may bring fine-tuned position tracking, grocery ads

    by 
    Steve Dent
    Steve Dent
    10.19.2012

    One way that sensors can track your position without using an array of satellites is by measuring your acceleration as you move around -- but unless you're piloting a jumbo jet, current devices aren't very accurate. Researchers at Caltech hope to change all that with a new, ultra-sensitive accelerometer they developed, which uses laser light to detect motion changes. The scientists managed to shrink a so-called large-scale interferometer down to micro-scale sizes, creating a device "thousands of times faster than the most sensitive sensors used today." That could allow a smartphone with such a micro-sensor to detect your exact position even while inside a grocery store, and flash "ads and coupons for hot dog buns" while you're in the bread aisle, according to Caltech. All that sounds good, but we can perhaps think of more inspiring uses for the new tech.

  • Deezmaker 3D Printer Store opens in Pasadena, will sell you a slice of the future for $600

    by 
    Jon Fingas
    Jon Fingas
    09.24.2012

    If the MakerBot store in Manhattan is the East coast's vanguard for 3D printer stores, Deezmaker's just-opened store in Pasadena, California is the equivalent pioneer for the West coast crew. As of now, you can walk through the doors at 290 North Hill Avenue and at least see the store's own Bukobot printer in action, even if high demand through Kickstarter pre-orders precludes walk-in sales for the next few weeks. When you can make that impulse purchase, however, you'll find the Bukobot at a relatively cheap $600 and may see some alternatives during your visit. Store owner and Bukobot creator Diego Porqueras stresses to Ars Technica that he wants Deezmaker lasting for the long haul, and he may have chosen just the right area to make that happen -- the shop is a stone's throw from the experimenters (and simply curious) at Caltech, NASA's JPL and Pasadena City College. No matter how it all shakes out, we're hoping that the two near-simultaneous store openings are the start of a larger trend that takes 3D printing into the mainstream.

  • Fake jellyfish made from rat cells have a place in our hearts (video)

    by 
    Jamie Rigg
    Jamie Rigg
    07.23.2012

    There's a whole sea of jellyfish out there ready to sting indiscriminately. So, why do we keep trying to make them? Scientists from Harvard and Caltech have a pretty good reason for creating fake jellies -- they hope to mend broken hearts by adapting their 'pumping' style of movement. Much like our own vital organ, the creatures are a mass of muscle adept at shifting fluid, meaning the research has several medical applications, such as bioengineered pacemakers for busted tickers. In creating the Medusoids, the team used a silicon scaffold coated in functional rat cardiac tissue, copying the muscle layout of a real jellyfish as best they could. When immersed in salt water and treated to bursts of current, the cells contract and cause the silicon sheet to move in a way eerily similar to the real thing. Next step for the team? An autonomous version that can move and potentially feed without their influence, of course. And, after seeing the little swimmers in action, we've certainly got palpitations. See what we mean after the break.

  • DNA-based artificial neural network is a primitive brain in a test tube (video)

    by 
    Terrence O'Brien
    Terrence O'Brien
    07.30.2011

    Many simpler forms of life on this planet, including some of our earliest ancestors, don't have proper brains. Instead they have networks of neurons that fire in response to stimuli, triggering reactions. Scientists from Caltech have actually figured out how to create such a primitive pre-brain using strands of DNA. Researchers, led by Lulu Qian, strung together DNA molecules to create bio-mechanical circuits. By sequencing the four bases of our genetic code in a particular way, they were able to program it to respond differently to various inputs. To prove their success the team quizzed the organic circuit, essentially playing 20 questions, feeding it clues to the identity of a particular scientist using more DNA strands. The artificial neural network nailed answer every time. Check out the PR and pair of videos that dig a little deeper into the experiment after the break.

  • Giant body of water found in space, black hole claims it was just hydrating

    by 
    Joseph Volpe
    Joseph Volpe
    07.23.2011

    Is that an intergalactic wave pool, or just a hungry, hungry quasar? Turns out it's a bit of both -- well, not the wave pool bit, but it's watery. A NASA-funded peep into the farthest reaches of the cosmos has uncovered this "feeding black hole" 12 billion light years away. APM 08279+5255, as this compacted mass of inescapable doom is affectionately known, has been gorging on water vapor and spewing out energy. How much H2O exactly? It's only the "largest and farthest reservoir of water ever detected in the universe," and it weighs in at 140 trillion times the amount in our oceans. Located via the cooperation of two teams of astronomers and their star-gazing equipment -- the Z-Space instrument at California Institute of Technology's Submillimeter Observatory in Hawaii and the Plateau de Bure Interferometer in the French Alps -- this aqueous discovery proves the wet stuff is more universally omnipresent than we once thought. Also, surfing aliens, right?

  • Paralyzed man can stand and walk again, thanks to spinal implant

    by 
    Amar Toor
    Amar Toor
    05.20.2011

    Here's an amazing story to end your week on a high note: a 25-year-old paraplegic is now walking again, thanks to a groundbreaking procedure developed by neuroscientists at the University of Louisville, UCLA and Cal Tech. The Oregon man, Rob Summers, was paralyzed below the chest in 2006, after getting hit by a speeding car. This week, however, doctors announced that Summers can now stand up on his own and remain standing for up to four minutes. With the help of a special harness, he can even take steps on a treadmill and can move his lower extremities for the first time in years. It was all made possible by a spinal implant that emits small pulses of electricity, designed to replicate signals that the brain usually sends to coordinate movement. Prior to receiving the implant in 2009, Summers underwent two years of training on a treadmill, with a harness supporting his weight and researchers moving his legs. This week's breakthrough comes after 30 years of research, though scientists acknowledge that this brand of epidural stimulation still needs to be tested on a broader sample of subjects before any definitive conclusions can be drawn. Summers, meanwhile, seems understandably elated. "This procedure has completely changed my life," the former baseball player said. "To be able to pick up my foot and step down again was unbelievable, but beyond all of that my sense of well-being has changed." We can only imagine.

  • Rescue robots map and explore dangerous buildings, prove there's no 'I' in 'team' (video)

    by 
    Amar Toor
    Amar Toor
    05.17.2011

    We've seen robots do some pretty heroic things in our time, but engineers from Georgia Tech, the University of Pennsylvania and Cal Tech have now developed an entire fleet of autonomous rescue vehicles, capable of simultaneously mapping and exploring potentially dangerous buildings -- without allowing their egos to get in the way. Each wheeled bot measures just one square foot in size, carries a video camera capable of identifying doorways, and uses an on-board laser scanner to analyze walls. Once gathered, these data are processed using a technique known as simultaneous localization and mapping (SLAM), which allows each bot to create maps of both familiar and unknown environments, while constantly recording and reporting its current location (independently of GPS). And, perhaps best of all, these rescue Roombas are pretty team-oriented. Georgia Tech professor Henrik Christensen explains: "There is no lead robot, yet each unit is capable of recruiting other units to make sure the entire area is explored. When the first robot comes to an intersection, it says to a second robot, 'I'm going to go to the left if you go to the right.'" This egalitarian robot army is the spawn of a research initiative known as the Micro Autonomous Systems and Technology (MAST) Collaborative Technology Alliance Program, sponsored by the US Army Research Laboratory. The ultimate goal is to shrink the bots down even further and to expand their capabilities. Engineers have already begun integrating infrared sensors into their design and are even developing small radar modules capable of seeing through walls. Roll past the break for a video of the vehicles in action, along with full PR.

  • Caltech sues Nokia, LG, others over camera patents

    by 
    Chris Ziegler
    Chris Ziegler
    12.01.2010

    Sure, your N8 might take a great picture -- but is it about to become a hotbed of legal wrangling between Espoo and one of the more prolific research universities in the States? We love us some heady courtroom drama, and Pasadena's Caltech is now officially attempting to bring the smack down on Nokia, LG, Pantech, Toshiba, STMicroelectronics, and others over a total of nine patents related to sensor technology (as far as we can tell, lens optics aren't involved). For its troubles, the university wants unspecified damages for infringing on the intellectual property... which, if it wins, we're hoping will be poured into its Jet Propulsion Laboratory. You know, because rockets are awesome.

  • Caltech research could lead to quantum hard drives, networks, parallel universes

    by 
    Darren Murph
    Darren Murph
    11.27.2010

    Quantum anything has typically fallen into our oft-used category of 'awesome things that'll never happen,' but if a crew of researchers at the California Institute of Technology have anything to say about it, they'll soon be changing the fortunes of that segment. The team has recently demonstrated quantum entanglement for a quantum state stored in four spatially distinct atomic memories, and while that probably just blew your mind a little bit, the breakdown is fairly interesting. Essentially, they've uncovered a quantum interface between the atomic memories, which is said to "represent something akin to a computer hard drive for entanglement." If extended, it could pave the way toward quantum networks, and in turn, massive webs of quantum computers. We're obviously decades out from understanding what this all means for the common computer user, but just remember this: "for an entangled quantum system, there exists no objective physical reality for the system's properties." And you thought The Matrix was deep.

  • da Vinci robot creators being sued by Caltech

    by 
    Darren Murph
    Darren Murph
    01.11.2007

    It's no secret that doctors ought to have a good bit of insurance on their side due to the flurry of medical malpractice (and similar) lawsuits that hit hospitals and surgeons everyday, but you know things are rough when robotic MDs get taken to court as well. Intuitive Surgical Inc., the creators of the da Vinci system for robotic surgery, has been sued by the California Institute of Technology, which claims that the system "infringes four patents held by the university." Obviously, Intuitive's CEO called the suit "outrageous and without merit," but the Pasadena school is nevertheless "seeking an injunction" and repayment for "damages." What's notable about the case, however, is where it was filed, as Tyler, Texas is quite a long ways from both institutions, but attorney's in the know have called the Lonestar State "a haven for patent pirates." Of course, there are rulings out there that are finally leaning the way of the tech firms at hand, suggesting that "obvious patent laws" should be relaxed somewhat, but it seems that even this probably won't mess with Texas. Nevertheless, let's just hope one of those lawyers doesn't end up under a (disgruntled) da Vinci knife one day.[Via RobotGossip]