maculardegeneration

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    Man receives someone else's reprogrammed stem cells

    by 
    Jon Fingas
    Jon Fingas
    04.02.2017

    The concept of using stem cells for transplants just became a truly practical reality: a Japanese man with age-related macular degeneration has received the first transplant of stem cells from another human donor. Doctors repurposed the donor's skin cells by turning them into induced pluripotent stem cells (that is, forced into a state where they can become many kinds of cells) that then became retinal cells. If all goes according to plan with the multi-step procedure, these fresh cells will halt the degeneration and preserve the patient's remaining eyesight.

  • Prototype glasses use video cameras, face recognition to help people with limited vision

    by 
    Dana Wollman
    Dana Wollman
    07.06.2011

    We won't lie: we love us a heartwarming story about scientists using run-of-the-mill tech to help people with disabilities, especially when the results are decidedly bionic. Today's tale centers on a team of Oxford researchers developing sensor-laden glasses capable of displaying key information to people with poor (read: nearly eroded) vision. The frames, on display at the Royal Society Summer Science Exhibition, have cameras mounted on the edges, while the lenses are studded with lights -- a setup that allows people suffering from macular degeneration and other conditions to see a simplified version of their surroundings, up close. And the best part, really, is that the glasses cull that data using garden-variety technology such as face detection, tracking software, position detectors, and depth sensors -- precisely the kind of tech you'd expect to find in handsets and gaming systems. Meanwhile, all of the processing required to recognize objects happens in a smartphone-esque computer that could easily fit inside a pocket. And while those frames won't exactly look like normal glasses, they'd still be see-through, allowing for eye contact. Team leader Stephen Hicks admits that vision-impaired people will have to get used to receiving all these flashes of information, but when they do, they might be able to assign different colors to people and objects, and read barcodes and newspaper headlines. It'll be awhile before scientists cross that bridge, though -- while the researchers estimate the glasses could one day cost £500 ($800), they're only beginning to build prototypes.

  • Telescopic eye implant approved by the FDA

    by 
    Joseph L. Flatley
    Joseph L. Flatley
    07.08.2010

    We love eye implants, and we've seen our share of them, and this one is pretty sweet (although it isn't the creepiest by a long shot -- that prize would go to the one that uses a human tooth to hold its lens). In the works for well over a year, and approved by the FDA a couple days ago, VisionCare Ophthalmic Technologies' implantable miniature telescope is intended for patients over 75 years of age who are suffering from end-stage macular degeneration. As with any tricky new surgery, this one is not without risks, including the need for a corneal transplant due to the device's size. According to CBC News, in clinical testing seventy-five percent of over 200 patients "had their vision improve from severe or profound impairment to moderate impairment," and there are two more studies on the way: one will follow up with existing patients, while the other will outfit 770 new patients with the device. The cost? $15,000.

  • British surgeons using radiation beams to halt macular degeneration

    by 
    Darren Murph
    Darren Murph
    11.23.2009

    We've seen more eyesight restoration efforts than we could easily count, but rather than tooting their horn about some theoretical discovery, boffins at Kings College Hospital in London are actually putting their hard work to use on real, live human brings. The new process, which goes by the name brachytherapy, is a one-off treatment for macular degeneration. In essence, surgeons carefully light up a beam of radiation within the eye for just over three minutes, which kills harmful cells without damaging anything else. A trial is currently underway in order to restore eyesight in some 363 patients, and everything thus far leads us to believe that the process is both safe and effective. As for costs? The procedure currently runs £6,000 ($9,889), but that's still not awful when you consider that existing treatments involving injections run £800 per month. Hop past the break for a video report.

  • VisionCare's implantable telescope will make you bionic, hopefully won't cost six million dollars

    by 
    Tim Stevens
    Tim Stevens
    04.03.2009

    The idea of a telescope fused directly into your eye may sound like a dream come true for impromptu stargazers, but the intent here is not for ocular astronomy. Rather it's to help those suffering from age-related macular degeneration, or AMD. This condition results in the deterioration of eyesight (much like the deterioration of cashflow in the other AMD), creating a large blind spot in the center of the field of vision. VisionCare's 4mm implantable telescope is intended to re-focus an image onto an undamaged part of the retina of one eye using either 2.2 or 3X magnification, giving patients the ability see directly ahead while leaving the other as it was to provide peripheral vision. It's a rather more simple solution than others we've seen, which is perhaps why it's already completed a Phase II/III clinical trial, and the FDA is recommending it be approved for use. We are too, if only so that we'll have more opportunities to use that Six Million Dollar Man soundboard we keep bookmarked -- that bionic jump never gets old.[Via Medgadget]

  • Bio-electronic implant seeks to restore partial sight

    by 
    Darren Murph
    Darren Murph
    03.12.2008

    We've seen initiatives all over the globe created in an attempt to beat blindness, but researchers based at MIT are feeling fairly confident that their development is within a few years of being able to "restore partial sight to people who have slowly gone blind because of degenerative diseases of the retina." The bio-electronic implant, which is about the size of a pencil eraser, would actually sit behind the retina at the back of the eyeball, and images would be transmitted to the brain "via a connector the width of a human hair." As it stands, an FDA grant application is already in the works, and the scientists are hoping to have it implanted in an animal as early as this summer. Still, the solution only works for folks who "were once able to see and have partially intact optic nerve cells" -- those who were blind from birth or suffer from glaucoma are unfortunately ineligible for the procedure.[Thanks, Rusty]

  • Researchers clear up TV watching for visually impaired

    by 
    Darren Murph
    Darren Murph
    01.16.2008

    Yeah, we've got HMDs for the visually impaired, but seriously, who's for sporting one of those things just to catch an afternoon soap? Thankfully, Dr. Eli Peli (and colleagues) from Harvard Medical School is lookin' out for said sect, and has developed a method for "enhancing the contrast of images of people and objects of interest on their digital televisions," which, during trials, was found to enhance legibility and overall enjoyment when watching. Furthermore, the technology is said to be the first to play nice with digital TV images, which seems fairly important considering that analog signals have but a few months to live here in America. Purportedly, the all-important modification that made the adjustments possible could be applied to HDTVs and digital STBs in the future, and sure enough, Peli has already sparked up conversation with Analog Devices in order to create a prototype chip for use in forthcoming sets. Now, if only clearing up those Get Smart reruns were this simple...[Via InventorSpot, image courtesy of Harvard (PDF)]