human-on-a-chip
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Alt-week 7.28.12: social mathematics, Pluto's moons and humans-on-a-chip
Alt-week peels back the covers on some of the more curious sci-tech stories from the last seven days. It's a beautiful world we live in. And, while the sweet and romantic part is debatable, strange and fantastic is not. Our universe is one populated by non-planetary celestial bodies with their own non-planetary satellites, high school social hierarchies based on predictable mathematical formulas and military-funded "gut-on-a-chips." It's a weird place filled with weird stories, and we just can't get enough of it. So, what has the last seven days brought us from the fringes of science and tech? Keep reading after the break to find out. This is alt-week.
Researchers create spinal cord connectors from human stem cells, heralding breakthrough
It's taken many years and more than a bit of brainpower, but researchers at the University of Central Florida have finally found a way to create neuromuscular connectors between muscle and spinal cord cells, using only stem cells. Led by bioengineer James Hickman, the team pulled off the feat with help from Brown University Professor Emeritus Herman Vandenburgh, who collected muscle stem cell samples from adult volunteers. After close examination, they then discovered that under the right conditions, these samples could be combined with spinal cord cells to form connectors, or neuromuscular junctions, which the brain uses to control the body's muscles. UCF's engineers say the technique, described in the December issue of the journal Biomaterials, marks a major breakthrough for the development of "human-on-a-chip" models -- systems that simulate organ functions and have the potential to drastically accelerate medical research and drug development. These junctions could also pay dividends for research on Lou Gehrig's disease or spinal cord injuries, though it remains unclear whether we can expect to see these benefits anytime soon.
