Air Guitar Pro, the VBeat instruments include "free style" and "easy go" modes, the latter of which allows for playing you fakestrument to pre-programmed rhythms -- a synergy of layered samples and a metronome, simply stunning. There's also a step-by-step learning mode called Pop Academy, but only losers need apply. These should sell for about £29.99 ($60 US) a piece, no word on availability. Action video is after the break.
[Via Coolest Gadgets]