David Jaffe had to say about the slew of Marvel comics games (specifically the ones featuring Spider-Man) that has been unleashed on the general populace (and continues to arrive). In short, Jaffe wants to see characters like Spidey put into a more story-driven game, rather than a giant, open world superhero playground that's solely focused on emulating the feel of having superpowers.
He's got a good point, one that's an all too common theme in superhero stories: Superhero gets powers, superhero spends all his time enjoying the rush of having said powers, superhero's uncle dies. Is that what you want from us Activision? Do you want our uncles to die?