Rocksmith. The game lets players strum through tunes by artists such as, David Bowie, Interpol, and The Rolling Stones using any real electric guitar they may have sitting around the house with a quarter-inch input jack.
As pointed out by internet sleuth supererogatory, the portfolio of illustrator Greg Korn reveals that the title is actually Guitar Rising, a piece of vaporware long in development at GameTank. Korn explains the project was "purchased by Ubisoft and currently in development for consoles." This certainly sounds like the very same thing.
The remaining mystery is how the guitar will track the notes plucked or strummed by players -- the Squier Stratocaster for Rock Band 3 can only do so using built-in semiconducters on each fret and a MIDI adapter. Is the game going to pick up on the actual note produced by the guitar? At the very latest, we'll find out when Rocksmith drops during the second half of 2011. For now, check out the screens and trailer below to get a feel for how cool you're going to look while playing.