stem cell
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Hitting the Books: How 'universal' stem cells might fix our brains
The technique of iPS cell reprogramming takes a differentiated cell backward in development.
Spay and neuter your pets -- and then bank their stem cells
Being man's best friend has a number of perks, one of which is that dogs get access to all the latest medical science, including, as it turns out, stem cell therapy. A company called Gallant is launching a new bank for canines nationwide (not called Barklays, alas) that allows you to cryopreserve your dog's stem cells for future use.
Google bans ads for unproven medical treatments
In an attempt to remain trustworthy, Google will no longer allow ads for "unproven or experimental medical techniques." Under the new Healthcare and medicines policy, the company will prohibit advertising for treatments that lack biomedical or scientific basis, including most stem cell therapies and gene therapy. That should cut down on ads for things like young blood transfusions and vampire facials.
Scientists bioprint living tissue in a matter of seconds
Bioprinting holds great potential for repairing injuries, testing drugs or replacing whole organs, but it's currently limited in complexity, viability and speed -- you can't just create tissue on a whim. Soon, though, it might be a matter of crafting whatever you need when you need it. Scientists at EPFL and University Medical Center Utrecht have developed an optical system that can bioprint complex, highly viable living tissue in "just a few seconds." It would represent a breakthrough compared to the clunky, layer-based processes of today.
Stem cell transplant offers hope for an HIV cure
There appears to be more than one promising sign in the quest for an HIV cure. Researchers have given a London patient a bone marrow stem cell transplant that has left him HIV-free for the past 18 months. As the donor has a very rare genetic mutation (CCR5 delta 32) that makes them HIV-resistant, the stem cells sent the HIV into remission with only a "mild reaction" from the treatment. It's a positive sign, and it suggests that the stem cell transplants that 'cured' Tim Brown in 2007 weren't just flukes.
Regenerative medicine pioneer continues changing lives with first successful laryngotracheal implants
Dr. Paolo Macchiarini is no stranger to world firsts, and less than a year after performing a synthetic windpipe transplant, the Karolinska Institute Professor has coordinated no less than two successful transplants of synthetic sections of larynx. Amazingly, both patients were able to breathe and talk normally straight after surgery, the basic functions we take for granted that they either struggled with or were simply unable to do before. The implants consisted of personally designed synthetic scaffolds coated with the candidates' own stem cells, so there's neither the chance of rejection nor the burden of life-long immunosuppressant therapy. Despite the amazing feat, Dr. Macchiarini ain't done yet, claiming this is the first of many steps towards building a synthetic, complete larynx -- voice box and all. Jump past the break for the official PR issued by Harvard Bioscience, the company responsible for growing what's in that tub.
Researchers create spinal cord connectors from human stem cells, heralding breakthrough
It's taken many years and more than a bit of brainpower, but researchers at the University of Central Florida have finally found a way to create neuromuscular connectors between muscle and spinal cord cells, using only stem cells. Led by bioengineer James Hickman, the team pulled off the feat with help from Brown University Professor Emeritus Herman Vandenburgh, who collected muscle stem cell samples from adult volunteers. After close examination, they then discovered that under the right conditions, these samples could be combined with spinal cord cells to form connectors, or neuromuscular junctions, which the brain uses to control the body's muscles. UCF's engineers say the technique, described in the December issue of the journal Biomaterials, marks a major breakthrough for the development of "human-on-a-chip" models -- systems that simulate organ functions and have the potential to drastically accelerate medical research and drug development. These junctions could also pay dividends for research on Lou Gehrig's disease or spinal cord injuries, though it remains unclear whether we can expect to see these benefits anytime soon.
Over the counter, spray-on stem cell treatment could heal burns on the go
Research at the University of Utah could lead to burn treatment on the go that makes use of your body's own cells. Surgeons Amit Patel and Amalia Cochran are researching the use of stem cells in conjunction with several chemicals as a spray-on jelly which has, in early testing, shown to accelerate the healing process of burns. While the team is starting with small burns, its goal is to be able to provide fast and effective, actual regeneration of a patient's own cells to be grafted onto large area burns. Video of the project is after the break.
Stem cell therapy restores British man's eyesight
Russell Turnbull, now 38, lost almost all the sight in his right eye after trying to break up a fight and being sprayed with ammonia 15 years ago. The result for him was what's known as Limbal Stem Cell Deficiency, which caused him great pain, the need for therapeutic treatment, and economic dependency. Good news for Russell is that he can put all that behind him now, after becoming one of the first recipients of a new stem cell grafting procedure, whereby healthy tissue from his left eye was implanted into his right and -- just like a video game medpack -- restored his vision to normal. For the moment, this treatment is limited to patients with at least one healthy eye, but given the pluripotent nature of stem cells, it is hoped that tissue from elsewhere in the body could one day be used to regenerate damaged parts, such as the cornea in this case. You may find further enlightenment in the video after the break.
Zii Trinity smartphone concept handled on video
It's an all too brief look, but it's infinitely more than we've seen so far. CNET Asia has managed some hands-on time the Zii Trinity concept smartphone. Quite a looker, and here we also get a glimpse of it next to the good ol' Zii Egg. As noted by the narrator, the bottom proprietary slot can be swapped for microUSB or mini-HDMI, there's a notably-sized 5 megapixel camera on the back, as well as one on the front for video conferencing. Enough talk, take a gander for yourself after the break. [Thanks, kumar]
Creative Zii EGG orders shipped, hands-on videos posted
It looks like somebody's Zii EGG orders have shipped, and we got the video to prove it. A staff member named DaHarder over at the DAP Review forums has just received one of the lusted-after devices, and luckily for us he's given it the ol' hands-on treatment and posted the evidence for our perusal. "The screen," he says, compares "very favorably" with the S Series Walkman, with colors described as bright and vibrant, even if the blacks leave something to be desired. And how about sound? He rates it as being "the best sounding Creative player" he's heard yet, "and that's without any EQ/Z-Fi etc." Not too shabby for a development model, eh? But that ain't all -- peep the videos after the break, and then hit the read link to jump in on the conversation your own self. [Via DAP Review]
Creative Zii EGG orders being processed, will ship by the end of the month
We still don't know what to make of Creative's Zii EGG and "stem cell computing" but it looks like we'll be getting our first answers relatively soon -- pre-order customers are being charged and told units will ship by the end of the month. As an added bonus, Creative is apparently including a free HD-out cable in these early deliveries, but we don't know if these are being pre-loaded with Android or that Plazma OS. Anyone else join the early adopter club? [Thanks, Joe]
Creative axes 2,700 jobs, simultaneously lowers expectations for Zii
While the hype is bubbling over surrounding Creative's Zii "stemcell computing," the outfit obviously doesn't think whatever it is will turn things around. Instead, it has chosen to cut some 2,700 jobs -- nearly half of its workforce -- as "demand for its music players tumbled." According to a report filed to Singapore's stock exchange on December 31, 2008, the company had 3,100 full time employees at the end of June 2008, which is around 47% lower than what was posted a year prior. 'Course, we suppose the cuts aren't all that surprising after posting a net loss of $19.7 million on the lowest revenues in five years, but it still makes us wonder just how confident the company is about this whole Zii dealio.[Thanks, Grayson]
DoD establishes institute tasked with regrowing body parts
Apparently not satisfied with simply building robotic body parts, the Department of Defense has now announced a brand new effort that it hopes will one day allow it to regrow actual body parts. Dubbed the Armed Forces Institute of Regenerative Medicine (or AFIRM), the new group will explore the use of stem cell research, among other things, to "reconstruct new skin, muscles and tendons, and even ears, noses and fingers." Or, as the Army surgeon general that'll be overseeing the program puts it: if an animal like a salamander can regrow a lost tail or limb, "Why can't a mammal do the same thing?" Not surprisingly, the institute apparently also won't be hard up for resources, with it boasting a budget of about $250 million for its first five-year period, and it enlisting the help of three universities, including Rutgers, Wake Forest, and the University of Pittsburgh. [Via Slashdot]
Researchers develop artificial nerve
Regular nerves getting you down? Why not try a bionic nerve? According to reports, researchers at the University of Michigan have developed an artificial nerve which could have the ability to bring damaged limbs and organs back to life. In a study published in the medical rag Experimental Neurology, Dr. Paul Kingham and his team at the UK Centre for Tissue Regeneration managed to take fat tissue from adult animals and differentiate them into nerve cells to be used for repair and regeneration. The team will repeat the study with human volunteers, and then develop an artificial nerve constructed from a biodegradable polymer. The "bio-material" will be rolled into a tube-like structure and inserted between two cut nerves, so that regrowing nerve fibers can spread from one end to the other. Next, the researchers hope to create a species of tyrannical man-bots called the Borg, whom they hope will move outward through the galaxy, assimilating all who stand in their way.[Via Slashdot]
