TransplantationMedicine
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Regenerative medicine pioneer continues changing lives with first successful laryngotracheal implants
Dr. Paolo Macchiarini is no stranger to world firsts, and less than a year after performing a synthetic windpipe transplant, the Karolinska Institute Professor has coordinated no less than two successful transplants of synthetic sections of larynx. Amazingly, both patients were able to breathe and talk normally straight after surgery, the basic functions we take for granted that they either struggled with or were simply unable to do before. The implants consisted of personally designed synthetic scaffolds coated with the candidates' own stem cells, so there's neither the chance of rejection nor the burden of life-long immunosuppressant therapy. Despite the amazing feat, Dr. Macchiarini ain't done yet, claiming this is the first of many steps towards building a synthetic, complete larynx -- voice box and all. Jump past the break for the official PR issued by Harvard Bioscience, the company responsible for growing what's in that tub.
